If you live on the east coast, you may be able to see the shuttle launch tonight at 9:20pm (source). As someone I know pointed out, there aren't many of these left from the current generation of space shuttle, so this may be worth checking out if you haven't seen one before. Apparently it is supposed to be visible anywhere from about a couple seconds to 2 minutes. Enjoy!
Update: The shuttle launch was scrubbed due to a hydrogen leak. Maybe next time!